The Chronic Effects of Carnitine on Recovery

Completed · Not applicable · Has a placebo group

Conditions studied: Muscle Soreness, Muscle Damage, Resistance Training, Oxidative Stress, Muscle Strength

In brief

This study investigated the effects of CarnipureTM, a high-quality L-carnitine ingredient, on long term (5 weeks) recovery, muscle damage, and SOD status in a population of males and females while training two days per week. The primary outcomes defining recovery were changes in serum creatine kinase levels and perceptual changes in recovery. Supporting variables included an assessment of strength and power as a functional indicator of recovery. This study would be the first to examine the effects of CarnipureTM on long-term recovery. Our primary hypothesis was that L-carnitine supplementation would reduce muscle damage and improve perceptual measures of recovery. Our secondary hypotheses were that L-carnitine supplementation would better sustain strength and power and elevate SOD status.

Key facts

Study ID

NCT04420377

Run by

Applied Science & Performance Institute

People needed

82

Starts

2020-03-02

Expected to finish

2020-06-12

Last updated by the study team

2021-02-03

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Participation in at least 30 minutes of moderate activity exercise 3 times per week

You may not qualify if…

• Body-mass index (BMI) of ≥ 30 kg/m²;
• Cardiovascular, metabolic, endocrine, or thyroid disease
• Smoking tobacco
• Drinking alcohol (>7 or >14 drinks per week for women and men, respectively)
• Pregnancy
• Hypertension
• Hyperlipidemia
• Hyperglycemia
• Thyroid disease
• Metabolic disease
• Type I or Type II Diabetes
• Use of anabolic-androgenic steroids
• Use of antioxidant supplements, NSAIDS, or nutritional supplements known to stimulate recovery or muscle mass gains, heart disease, prescription medications, dietary supplements that enhance muscle strength or muscle recovery

Where it is running

• The Applied Science and Performance Institute — Tampa, Florida, United States

Full record on ClinicalTrials.gov

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