CBD-Microglia PET Study

Completed · Early Phase 1 · Has a placebo group

Conditions studied: CBD, Healthy

In brief

This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.

Key facts

Study ID

NCT04398719

Run by

Yale University

People needed

28

Starts

2021-05-07

Expected to finish

2024-12-11

Last updated by the study team

2026-04-29

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men and women aged 18- 55 years
• No significant medical or neurological illness
• No implanted metal devices that may pose a risk during MRI scanning
• Within the annual permissible radiation exposure
• Able to provide written informed consent.

You may not qualify if…

• Current use of any medications
• Presence of metal in the body
• Pregnancy or lactation

Where it is running

• Connecticut Mental Health Center — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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