SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training

Recruiting now · Not applicable

Conditions studied: Chronic Asthma

In brief

The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.

Key facts

Study ID

NCT04395937

Run by

University of Liege

People needed

100

Starts

2020-09-01

Expected to finish

2028-09-01

Last updated by the study team

2026-04-14

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• asthmatic patient
• aged 18- 65 years
• ACQ > 1.5
• stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene

You may not qualify if…

• IMC > 35
• severe osteoarthritis of the knees and hips
• unstable angor
• Severe uncontrolled hypertension

Where it is running

• Chu Liege — Liège, Liege, Belgium (enrolling)

Full record on ClinicalTrials.gov

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