Stress, Emotion Regulation, and Alcohol in Women Veterans

Completed · Not applicable

Conditions studied: Alcohol Use Disorder, Post Traumatic Stress Disorder

In brief

The purpose of the study "Stress, Emotion Regulation, and Alcohol in Women Veterans" is to learn about the effects of negative emotion and stress on behavior (including alcohol use) among women Veterans, including women with and without posttraumatic stress disorder. Additionally, the study looks at whether a woman's use of emotion regulation techniques changes the association between stress or negative emotion and behavior. Lastly, the study examines how women's reactions to stress, and the effects of stress, vary across the menstrual cycle - depending on the level of circulating hormones.

Key facts

Study ID: NCT04393623
Run by: VA Office of Research and Development
People needed: 81
Starts: 2020-11-01
Expected to finish: 2024-09-30
Last updated by the study team: 2026-02-27

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Current alcohol misuse, defined as scoring 3 or higher on the AUDIT-C
If using other illicit substances, alcohol is their primary substance of use
Alcohol use in the past 45 days
Able to write and speak in English
Served in the U.S. Military
Willing to provide blood samples at laboratory sessions to assay hormone levels and take urine ovulation tests at home

You may not qualify if…

Psychotic symptoms or uncontrolled Bipolar Disorder (screened for during session 1 using SCID-5 screening modules)
Brain damage or were in an accident that affects ability to complete the computerized task
Current (past 3 months) active suicidal ideation or intent
Current pregnancy

Where it is running

VA Central Western Massachusetts Healthcare System, Leeds, MA — Leeds, Massachusetts, United States

Full record on ClinicalTrials.gov

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