IMPact of Donor Heart Function on Recipient Outcomes - a prospectiVE Study to Increase the Utilization of Donor HEARTs
Recruiting now
Conditions studied: Heart Transplantation
In brief
Severe heart failure is a diagnosis with a very poor prognosis. Heart transplantation is the best treatment for terminal heart failure but this type of treatment is limited by the number of available organs. About 20-25% of possible donor hearts are not considered for transplantation because they have some form of functional impairment. The functional impairment affecting organ donors is, however, usually reversible. A number of retrospective studies show that cardiac function recovers and recipients of hearts with dysfunction do not have worse outcomes compared to recipients of hearts with perfect cardiac function. However, there are no prospective studies on whether the functional impairment of the donor heart is of significance for the recipient. With a systematic and simple investigation of the heart, it should be possible to identify the hearts that are safe to transplant. This will thus increase the number of available donors.
Key facts
- Study ID
- NCT04393181
- Run by
- Vastra Gotaland Region
- People needed
- 500
- Starts
- 2022-04-05
- Expected to finish
- 2027-04-01
- Last updated by the study team
- 2022-05-02
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient who has been accepted for heart transplantation at the participating transplantation center
- The research subject has given written consent to participate in the study
- Aged 18 years or older
You may not qualify if…
- • Mental inability, reluctance or language difficulties that result in difficulty understanding the meaning of study participation
- Another study, where the patient is included, which is not considered compatible with the current study.
Where it is running
- Sahlgrenska University Hostpial — Gothenburg, Västra Götaland County, Sweden (enrolling)
Full record on ClinicalTrials.gov
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