Effect of Acute Dietary Supplementation With Grape Seed Extract on Aortic Stiffness, Arterial Pressure, and Blood Vessel Dilation in Collegiate Obese Individuals at Rest

Completed · Not applicable · Has a placebo group

Conditions studied: Obesity

In brief

This study investigated if elevated BP and aortic stiffness characterized in obese individuals are attenuated following acute grape seed extract supplementation. It is hypothesized that acute dietary supplementation with grape seed extract attenuates aortic stiffness, systolic blood pressure, diastolic blood pressure, mean arterial pressure, and total peripheral resistance and these effects are partially due to reductions in peripheral vasoconstriction

Key facts

Study ID

NCT04389060

Run by

California Baptist University

People needed

20

Starts

2019-03-01

Expected to finish

2020-03-01

Last updated by the study team

2020-05-15

Who can join

Age: 18 and older, up to 29. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Obesity: body mass index (>30), Normal body weight: body mass index (25-29)

You may not qualify if…

• cardiovascular diseases or consume any antihypertensive medication or supplementation that can affect blood pressure or aortic stiffness

Where it is running

• California Baptist University — Riverside, California, United States

Full record on ClinicalTrials.gov

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