Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Completed

Conditions studied: Sickle Cell Disease, Renal Disease, Glomerular Disease

In brief

The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients

Key facts

Study ID

NCT04380610

Run by

University of Alabama at Birmingham

People needed

120

Starts

2021-05-12

Expected to finish

2025-06-30

Last updated by the study team

2025-09-18

Who can join

Age: 5 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• SCA patients (HbSS and SB0 thalassemia)
• Age: 5.0-50.0 at enrollment

You may not qualify if…

• Recent SCA complication associated with hospitalization (within 30 days) or ED visit (within 14 days)
• Current AKI defined as >0.3mg/g increase in SCr from prior visit
• Known history of anaphylaxis with contrast agent or known pregnancy

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of Illinois Chicage — Chicago, Illinois, United States
• St Jude Childrens Research Hospital — Memphis, Tennessee, United States
• University of Tennessee Health Science Center — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.