Individualized Assessment and Treatment for TMD
Recruiting now · Not applicable
Conditions studied: Temporomandibular Joint Disorders, Orofacial Pain
In brief
Temporomandibular/orofacial pain disorders (TMD) are a group of painful conditions with multiple determinants.This proposal has two main goals: 1) to test a highly individualized, adaptive treatment for TMD that has potential to be more effective than other psychosocial treatments; and 2) to discover the mechanisms by which psychosocial treatments work in chronic pain. TMD patients (N=160) will be randomized to receive standard care (STD) + an individualized assessment and treatment program (IATP) or to standard care + conventional cognitive-behavioral treatment (STD+CBT). It is expected that the STD+IATP treatment will yield lower pain, depression and interference scores over time than STD+CBT, and that changes in coping ability will mediate the treatment effects on outcomes.
Key facts
- Study ID
- NCT04376333
- Run by
- UConn Health
- People needed
- 160
- Starts
- 2021-02-03
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-07-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age > 18 years
- Jaw pain > 3 mo; > 3/10 on pain scale
- Positive Axis I diagnosis on the Diagnostic Criteria for temporomandibular disorders (DC/TMD), with or without disc displacement
- Positive on > 1 of:
- Any myalgia diagnosis
- Any myofascial diagnosis
- Arthralgia
- TMD-related Headache
You may not qualify if…
- Lack of fluency in English
- Previous invasive surgery for TMD, not including arthrography or arthrocentesis
- Extensive anatomical destruction or deterioration of the TM joint
- Diagnosed as having pain of neuropathic or odontogenic origin
- Carrying a diagnosis of psychosis
- Taking narcotic pain medication
- Any comorbid condition necessitating use of an intraoral appliance (e.g., obstructive sleep apnea)
- Pregnancy (excluded due to prescription of NSAIDs)
Where it is running
- UConn Health — Farmington, Connecticut, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.