Prednisolone Treatment in Acute Interstitial Nephritis

Recruiting now · Phase 4

Conditions studied: Acute Tubulo-Interstitial Nephritis

In brief

A Prospective randomized trial with a primary objective to investigate the effect ofprdenisolone treatment in acute interstitial nephritis

Key facts

Study ID

NCT04376216

Run by

Region MidtJylland Denmark

People needed

110

Starts

2017-09-01

Expected to finish

2027-09-01

Last updated by the study team

2020-12-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Biopsy verified AIN
• Clinical suspicion of AIN
• Age > 18 years
• One of following criteria:
• Plasma creatinine > 120 µmol/L or
• Plasma creatinine increase > 30 µmol/L or increase > 50 % of baseline plasma creatinine
• Fertile women are included

You may not qualify if…

• No ability to give informed consent
• Immunosuppressive treatment (including prednisolone) within 3 months before biopsy
• Autoimmune disease
• Prednisolone intolerance
• Pregnancy or lactation
• Active cancer (except basal cell carcinoma)
• Short life expectancy (< 6 months)
• CKD stage IV-V
• AIN secondary to or accompanied by glomerulonephritis, sarcoidosis or inherited interstitial renal disease
• Previous participation Withdrawal criteria
• Development of exclusion criterion
• Withdrawal of consent

Where it is running

• Godstrup Hospital — Herning, Denmark (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.