A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

Stopped early · Phase 4 · Has a placebo group

Conditions studied: Pain, Postoperative

In brief

the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus US guided QL catheters

Key facts

Study ID

NCT04368364

Run by

The University of Texas Health Science Center, Houston

People needed

3

Starts

2020-05-22

Expected to finish

2020-06-29

Last updated by the study team

2022-05-16

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Elective C section via Pfannenstiel incision
• Living singleton pregnancy
• Gestation week at least 37 weeks
• American Society of Anesthesiologists (ASA) status 1, 2 and 3
• Primary and secondary C sections

You may not qualify if…

• Chronic pain
• Opioid tolerant patients
• Allergy to drugs used in the study.
• Cognitive dysfunction
• BMI > 40
• Coagulation disorder
• Local infection
• Inability to tolerate oral medication
• Previous intra-abdominal surgery
• Patients who will receive a combined spinal epidural for their C section
• Local anesthetics injected at any other fascial plane except the QLB plane (for e.g.- local wound infiltration by surgeon)
• Patients who received sedation or general anesthesia during their C section (midazolam, ketamine, fentanyl, propofol, hydromorphone)

Where it is running

• Memorial Hermann Hospital TMC — Houston, Texas, United States
• The University of Texas Health Science Center at Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.