Variability of Heart Rate as a Marker of Complication of Colorectal Surgery
Recruiting now
Conditions studied: Surgery--Complications
In brief
Heart rate variability reflects the autonomic nervous system on the intrinsic activity of sinus node cells. Sympathetic hyperactivity is an adaptation to stress, while parasympathetic hyperactivity is present at rest. Thus, any variability in the heart frequency rate reflects variations in sympathetic and parasympathetic components in the autonomic nervous system. Failure to return to normal or a reduction in the variability of the heart rate in the postoperative period is correlated with complications in colorectal surgery.
Key facts
- Study ID
- NCT04367987
- Run by
- Centre Hospitalier Universitaire de Nīmes
- People needed
- 117
- Starts
- 2020-06-17
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-06-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients operated for a scheduled colorectal resection due to cancer, diverticulitis, or Chronic Inflammatory Bowel Disease,
- American Society of Anesthesiologists score 1-2
- The patient must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
You may not qualify if…
- Patient taking antidepressants, antipsychotics, antihypertensive beta blocker type, anti-arythmic or oral contraception
- Uncontrolled diabetes or associated with a neuropathy
- Arrhythmias and conduction disturbances, , coronaropathy and heart failure, kidney failure
- Neuropathies
- Pacemaker or defibrillator
- The subject is participating in another interventional study, or is in a period of exclusion determined by a previous study
- The subject refuses to sign the consent
- It is impossible to give the subject informed information
- The patient is under safeguard of justice or state guardianship
Where it is running
- CHU de Nimes — Nîmes, France (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.