Prospective Study to Validate Ablation Parameters with MRI Based Scar for Left Atrial Ablation
Completed
Conditions studied: Atrial Fibrillation
In brief
One of the goals of an ablation procedure is to create scarring of cardiac tissue. Not all ablations result in scar tissue. Advances in technology have improved scarring but ideal parameters that result in scar tissue are still not completely clear and there is great variability in the parameters used. Theoretically, intense ablation can always create scar tissue but is also likely to create more complications such as cardiac perforations. The investigator recently published another retrospective study looking at ablation parameters that reliably result in scar tissue but it had its limitations as it was retrospectively done. This is a prospective study to validate the parameters that result in long term scarring. MRI has long been used to visualize ablation scar tissue. So in this study patients undergoing, initial left atrial ablation for atrial fibrillation as standard of care will undergo a 3 month post ablation MRI and that will be used to validate the ablation parameters.
Key facts
- Study ID
- NCT04363307
- Run by
- Ravi Ranjan
- People needed
- 64
- Starts
- 2020-05-14
- Expected to finish
- 2023-07-31
- Last updated by the study team
- 2024-11-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Paroxysmal or early Persistent AF (continuous AF duration less than 3 months and CHADSVASC great than or equal to 2).
- First time ablation for AF
- Agreeable to a 3 month MRI
You may not qualify if…
- Claustrophobic (unable to undergo MRI)
- Having undergone prior left atrial ablation including AT or atypical flutter
- Metal implants that preclude getting an MRI
- eGFR < 30
Where it is running
- University of Utah Health Sciences Center — Salt Lake City, Utah, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.