Gargling and Nasal Rinses to Reduce Oro- and Nasopharyngeal Viral Load in Patients With COVID-19

Withdrawn before enrolling · Phase 2

Conditions studied: COVID-19

In brief

For this study, 48 patients who have been diagnosed with COVID-19 will be randomly assigned to four study groups: control, saline, chlorhexidine gluconate, and povidone-iodine. Each patient will be asked to gargle with a solution of either saline, chlorhexidine gluconate, or povidone-iodine or nothing (control group) as well as spray the same solution in their nose four times daily. Patients will then be tested for COVID-19 once daily in the evening for 7 days and viral loads will be measured.

Key facts

Study ID

NCT04344236

Run by

NYU Langone Health

People needed

0

Starts

2020-04-09

Expected to finish

2020-05-09

Last updated by the study team

2021-05-10

Who can join

Age: 18 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Positive test for COVID-19
• Age 18-79 years
• Willing and able to perform oral gargles and nasal rinses four times daily

You may not qualify if…

• Requiring mechanical ventilation
• Unable or unwilling to perform oral gargles and nasal rinses four times daily
• History of chronic upper respiratory tract disease
• Known iodine allergy
• History of thyroid disease

Where it is running

• NYU Langone Health — New York, New York, United States

Full record on ClinicalTrials.gov

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