Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation

Completed · Not applicable

Conditions studied: COVID, Corona Virus Infection

In brief

The purpose of this study is to examine the impact of ascorbic acid (vitamin c) and zinc gluconate in reducing duration of symptoms in patients diagnosed with coronavirus disease 2019 (COVID-19). Patients above the age of 18 who present to the Cleveland Clinic outpatient testing and receive a positive test for COVID-19 will be invited to participate.

Key facts

Study ID

NCT04342728

Run by

The Cleveland Clinic

People needed

214

Starts

2020-04-08

Expected to finish

2021-02-11

Last updated by the study team

2021-02-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Outpatients ≥ 18 years presenting to Cleveland Clinic Health System in Ohio and Florida who test positive for COVID-19 having any of the following symptoms
• Fever or chills
• Shortness of breath or difficulty breathing
• Cough
• Fatigue
• Muscle or body Aches
• Headache
• New loss of taste
• New loss of smell
• Congestion or runny nose
• Nausea
• Vomiting
• Diarrhea
• Women of child bearing potential:
• have had a menstrual period within the past 30 days, or
• have had previous sterilization, or
• are perimenopausal (less than 1 year) who have a negative pregnancy test, or
• women of childbearing potential who do not meet the above and have a negative pregnancy test.

You may not qualify if…

• Patients who are found to be positive during hospitalization
• Patients who reside outside Ohio or Florida.
• Pregnant women:
• Current known pregnancy
• Positive pregnancy test (women of child bearing potential who have not had previous sterilization as defined as hysterectomy or tubal ligation)
• Women of childbearing potential who do not meet the above criteria, last menstrual period greater than 30 days and have a positive pregnancy test.
• Lactating Women
• End stage kidney disease
• Advanced liver disease awaiting transplant
• History of Calcium Oxalate kidney stones.

Where it is running

• Cleveland Clinic — Weston, Florida, United States
• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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