Brain Effects of Opiate Agonist and Antagonist

Completed · Phase 4

Conditions studied: Chronic Low-back Pain

In brief

This study will look at the short-term effect of morphine on brain response to food.

Key facts

Study ID

NCT04342130

Run by

University of Rochester

People needed

10

Starts

2018-04-27

Expected to finish

2019-04-16

Last updated by the study team

2021-05-07

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy participants
• Patients in pain: suffering from persistent pain more days than not, 3/10 in intensity on a numerical rating scale, for at least 6 weeks or more.

You may not qualify if…

• Any DSM diagnosis
• diabetes
• food allergies
• lactose intolerance
• participants seeking to quit smoking or to lose weight
• participants on any psychotropic medication including opiate based analgesics (e.g. oxycodone, methadone, suboxone)
• pregnant or nursing women
• pacemaker or other implanted electrical devices
• Participants with a past history of head trauma or seizures
• Any past history of illegal drug or alcohol misuse
• Participants who cannot undergo an MRI scan.

Where it is running

• Yale University — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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