Reminder Focused Positive Psychiatry in Adolescents With ADHD and PTSD

Completed · Not applicable

Conditions studied: Posttraumatic Stress Disorder, Attention Deficit Hyperactivity Disorder

In brief

This feasibility study investigates the impact of reminder-focused-positive-psychiatry (RFPP) on attention-deficit-hyperactive-disorder (ADHD) and posttraumatic-stress-disorder (PTSD) symptoms, vascular-function, inflammation and well-being of adolescents with comorbid ADHD \& PTSD. In this randomized clinical trial, 24 subjects with comorbid ADHD and PTSD, aged 12-18 years old, free of known medical and other major psychiatric disorders, will be recruited from the pool of eligible subjects at Los Angeles and Kern County Children Mental Health Centers (\>1500 subjects) after obtaining informed consent from parents as well as subjects' assentment. Commonwealth and Oswell Kern County Mental Health Clinic will be used for subjects enrollment, randomization as well as study implementation from trauma disorder clinic. Kern Medical will be used for manuscript write up and analyses. Adolescents will be randomized to: group-RFPP or trauma-focused group-cognitive-behavioral-therapy (TF-CBT). Participants will complete twice-weekly-intervention for 6-weeks-trial. The group-RFPP-intervention will be inclusive of RFPP interventions on a) traumatic-reminders, and b Avoidance \& negative-cognition. Vascular-function-measured as temperature-rebound (TR), C-reactive-protein (CRP), homocysteine, SNAP-questionnaire, Clinician-Administered PTSD-Scale-children-version (CAPS-CA) and neuropsychiatric-measures will be measured at baseline and 6th week. Subjects will be followed for 12 months. Parents and subjects will be informed of the risks associated with use of venipuncture and loss of confidentiality of collected information.

Key facts

Study ID

NCT04336072

Run by

University of California, Los Angeles

People needed

11

Starts

2017-01-10

Expected to finish

2019-06-29

Last updated by the study team

2026-03-30

Who can join

Age: 9 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English speaking Boy/Girl Age 9 - 18 years old
• Able to read/write in English
• Documented ADHD and PTSD, and parents provided informed consent

You may not qualify if…

• Psychotic or Mood Disorders or Self-injurious behavior
• Cognitive disorder or other neurodevelopmental disorders
• Diagnosis of substance use disorder

Where it is running

• UCLA Kern — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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