Crossover Comparison of Tidal Volume Delivery During Nasal Intermittent Positive Pressure Ventilation in Preterm Infants: Infant Cannula vs. Nasal Continuous Positive Airway Pressure Prongs

Status unconfirmed · Not applicable

Conditions studied: Respiratory Distress Syndrome in Premature Infant

In brief

Crossover bedside clinical study to examine relative tidal volume delivery during nasal intermittent positive pressure ventilation (NIPPV) and directly compare the RAM® infant cannula to a nasal continuous positive airway pressure (nCPAP) delivery system in vivo. The study population will consist of preterm neonates with mild respiratory insufficiency who are receiving NIPPV, non-invasive neurally adjusted ventilatory assist (NIV NAVA), or nCPAP.

Key facts

Study ID

NCT04326270

Run by

Arkansas Children's Hospital Research Institute

People needed

20

Starts

2019-03-07

Expected to finish

2020-06-30

Last updated by the study team

2020-03-30

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chronologic age less than 28 days
• Gestational age at birth between 24 weeks 0 days to 34 weeks 6 days
• Currently receiving NIPPV, NIV NAVA, or nCPAP

You may not qualify if…

• Oxygen requirement greater than 40%
• Peak inspiratory pressure greater than 20 cm H2O
• Major congenital anomalies of the heart or lungs

Where it is running

• Arkansas Children's Hospital — Little Rock, Arkansas, United States (enrolling)

Full record on ClinicalTrials.gov

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