Immunopathological Analysis in a French National Cohort of Membranous Nephropathy

Recruiting now · Not applicable

Conditions studied: Membranous Nephropathy

In brief

National cohort of all cases of membranous nephropathy (MN) during a 1 year period in France, based on a pathological and/or serological diagnostic, collecting the data on: * incidence of MN * prevalence of anti-PLA2R1 and anti-THSD7A * clinical outcome one year after diagnosis or after relapse (complete remission, partial remission or persistent nephrotic syndrome) * environmental risk factors for the onset of MN * HLA markers * patient care status in France

Key facts

Study ID

NCT04326218

Run by

Centre Hospitalier Universitaire de Nice

People needed

400

Starts

2020-07-04

Expected to finish

2031-12-03

Last updated by the study team

2026-06-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or more
• Biopsy on a native kidney consistent with MN and/or positivity for serum anti-PLA2R1 and/or anti-THSD7A antibodies
• Signed informed consent

You may not qualify if…

• Diagnosis error based on the kidney biopsy staining or on serology analyses for the positivity for anti-PLA2R1 and/or anti-THSD7A
• Patients unable to give an informed consent
• Patients withdrawing an informed consent

Where it is running

• CHU de Nice, Hôpital de l'Archet — Nice, Alpes Maritime, France (enrolling)

Full record on ClinicalTrials.gov

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