Hantavirus Registry - HantaReg
Recruiting now
Conditions studied: Hantavirus Infections, Hemorrhagic Fever With Renal Syndrome, Nephropathia Epidemica, Hantavirus Cardiopulmonary Syndrome
In brief
Hantavirus disease are zoonotic infections and remain a clinical challenge with globally increasing incidence and multiple serious outbreak situations in Europe within the last years. Hantavirus disease encompasses two clinical syndromes, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) caused by Old World and New World hantaviruses, respectively. Depending on the causative Old World hantavirus species, clinical course of HFRS can vary from mild to moderate to severe. At present, there is no specific therapy available for hantavirus disease. As the clinical course of hantavirus disease is dependent on the causing viral pathogen and as there worrisome hints that clinical course HFRS and HCPS overlap, further studies with regard to the disease course are mandatory. Furthermore, the examination of attributable mortality and costs of hantavirus disease will need to be studied on a multinational basis and therefore HantaReg will particularly use a matched case control design.
Key facts
- Study ID
- NCT04323904
- Run by
- University of Cologne
- People needed
- 200
- Starts
- 2020-03-04
- Expected to finish
- 2030-12-01
- Last updated by the study team
- 2025-12-17
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Serological or molecular evidence of hantavirus infection and clinical evidence of nephropathia epidemica or hemorrhagic fever with renal syndrome (HFRS)
- Serological or molecular evidence of hantavirus infection and clinical evidence of hantavirus cardiopulmonary syndrome (HCPS)
You may not qualify if…
- Serological or molecular evidence of hantavirus infection without clinical signs of nephropathia epidemica, HFRS or HCPS
Where it is running
- University Hospital of Cologne — Cologne, North-Rhine Westfalia, Germany (enrolling)
Full record on ClinicalTrials.gov
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