Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation

Completed

Conditions studied: Mechanical Ventilation

In brief

The overall objective of the study is to conduct an observational study involving intensive care unit patients receiving mechanical ventilation and determine if there are differences in diaphragm thickness ultrasound measurements during expiratory and inspiratory phases in a controlled and spontaneous mode. For patients receiving sedatives, an additional set of measurements will be taken during a standard of care interruption of sedatives

Key facts

Study ID

NCT04319939

Run by

University of Chicago

People needed

66

Starts

2020-02-05

Expected to finish

2022-04-11

Last updated by the study team

2025-12-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients > 18 years of age
• intubated and mechanically ventilated for < 48 hours at the time of screening

You may not qualify if…

• pregnancy
• history of diaphragmatic paralysis
• neuromuscular blockade
• cardiac arrest

Where it is running

• The University of Chicago Medical Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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