Comparison of Training Load With/Out Blood Flow Restriction Training in Rheumatoid Populations

Stopped early · Not applicable

Conditions studied: Rheumatoid Arthritis, Myositis, Osteoarthritis, Weakness, Muscle

In brief

The study will investigate the effects of a traditional, high-intensity strengthening program compared to an investigational low-intensity strengthening program that also uses blood flow restriction as part of the training program. Both groups will be compared to a control group, which will receive no training. Measures of strength, function, and patient outcomes will be taken before starting the training, at mid-term, and at the end of the 8-week training program. Additionally, investigators will collect outcome data at 6 and 12 months after completing the program to assess for long term outcomes. The eligible populations are participants with rheumatoid arthritis (RA), osteoarthritis (OA), or myositis. The study will include about 15 participants per group, or 45 people with each diagnosis.

Key facts

Study ID

NCT04309227

Run by

Louisiana State University Health Sciences Center Shreveport

People needed

4

Starts

2021-05-01

Expected to finish

2023-08-23

Last updated by the study team

2024-01-22

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diagnosis from LSUHSC-SHreveport Rheumatologist of rheumatoid arthritis (RA), osteoarthritis (OA), or myositis
• stable medication for at least 3 months
• OA in weightbearing joints, and limited to non-advanced OA per Kellgren Lawrence grading
• cleared by rheumatologist for participation in high intensity training and blood flow restriction training

You may not qualify if…

• cardiovascular or other disease preventing exercise participation
• within past 6 months, have performed regular physical activity training or physical therapy
• one or more arthroplasty in weight-bearing joints
• taking more then 5mg of prednisone in past 3 months
• unable to perform timed up and go test, 10 meter walk test, or 6 minute walk test without more than supervision assistance; assistive devices can be used

Where it is running

• LSUHSC-Shreveport — Shreveport, Louisiana, United States

Full record on ClinicalTrials.gov

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