Does Medical Cannabis Reduce Opioid Use in Adults With Pain

Completed

Conditions studied: Opioid Use, Marijuana, Chronic Pain

In brief

The study will examine how medical cannabis use affects opioid analgesic use. This landmark study will be among the first to examine the effect of medical cannabis with different THC/CBD (Tetrahydrocannibinol/Cannabidiol) content on opioid use as well as adverse events.

Key facts

Study ID

NCT04308148

Run by

Albert Einstein College of Medicine

People needed

217

Starts

2020-10-06

Expected to finish

2024-03-13

Last updated by the study team

2024-03-25

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At least 18 years of age
• English or Spanish fluency
• Actively certified for medical cannabis
• Intends to have a soft-gel capsule product dispensed at Vireo
• Medical cannabis qualifying conditions or complications of "chronic or severe pain" or "pain that degrades health and functional capability as an alternative to opioid use or substance use disorder"
• Joint or neuropathic pain
• Current severe pain
• Dispensed opioid analgesics within the last 60 days
• To maintain the integrity of the study, we do not disclose all inclusion criteria to potential participants.

You may not qualify if…

• Inability to provide informed consent
• Inability to complete study visits over 14 weeks
• Terminal illness
• Current or prior psychotic disorder
• Buprenorphine or methadone treatment for opioid use disorder within the past year
• Allergies to tapioca or coconut
• Currently pregnant, planning to become pregnant within the next 3 months, or breastfeeding
• Condition that is considered by a pharmacist or medical provider to be a contraindication to medical cannabis use (e.g. unstable cardiac arrhythmia or specific drug-use interaction)

Where it is running

• Montefiore Health System — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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