STRIVE Post-Market Registry Study

Recruiting now

Conditions studied: Emphysema

In brief

This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-market setting.

Key facts

Study ID

NCT04302272

Run by

Olympus Corporation of the Americas

People needed

150

Starts

2021-10-09

Expected to finish

2029-10-01

Last updated by the study team

2026-08-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients with shortness of breath and hyperinflation associated with severe emphysema and evidence of low collateral ventilation.
• Subjects must understand and voluntarily sign an informed consent form.

You may not qualify if…

• Subjects who are not appropriate for SVS therapy based upon the US FDA-approved IFU requirements.
• Subjects who were withdrawn from this study for any reason will not be allowed to re-enroll.
• Subjects who have incomplete screening or baseline data.

Where it is running

• Dignity Health St. Joseph's Hospital and Medical Center — Phoenix, Arizona, United States (enrolling)
• El Camino, Taft Center for Clinical Research — Mountain View, California, United States (enrolling)
• University of Miami — Coral Gables, Florida, United States (enrolling)
• Northwestern University, Division of Pulmonary and Critical Care Medicine — Chicago, Illinois, United States (enrolling)
• University of Chicago — Chicago, Illinois, United States (enrolling)
• LSU Health Shreveport — Shreveport, Louisiana, United States (enrolling)
• University of Maryland — Baltimore, Maryland, United States (enrolling)
• Beth Israel Decaconess — Boston, Massachusetts, United States (enrolling)
• Memorial Hospital at Gulfport — Gulfport, Mississippi, United States (enrolling)
• Duke University Medical Center — Durham, North Carolina, United States (enrolling)
• Penn State Milton S. Hershey Medical Center — Hershey, Pennsylvania, United States (enrolling)
• Temple University — Philadelphia, Pennsylvania, United States (enrolling)
• AnMed Health — Anderson, South Carolina, United States (enrolling)
• Baylor Scott & White Research Institute — Dallas, Texas, United States (enrolling)
• University of Texas Southwestern — Dallas, Texas, United States (enrolling)
• University of Texas Health Science Center at Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

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