Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery

Completed · Early Phase 1

Conditions studied: Submandibular Gland Tumor, Parotid Gland Tumor

In brief

The purpose of this study is determine salivary gland disposition of d-limonene, the primary component in citrus peel and a common dietary supplement. Salivary gland tissue and saliva will be collected to determine concentration of d-limonene and its metabolites in these tissues.

Key facts

Study ID

NCT04296266

Run by

Stanford University

People needed

10

Starts

2016-02-01

Expected to finish

2017-12-21

Last updated by the study team

2020-03-05

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Elected to undergo surgery for recent diagnosis of parotid or submandibular gland tumor
• Ability to adhere to study visit schedule and other protocol requirements
• Operable candidate base on the surgeon's note
• Ability to understand and the willingness to sign a written informed consent document

You may not qualify if…

• Nursing or pregnant
• Diagnosis of kidney disease, history of renal disease with creatinine > 1.5 mg/dL, or currently on dialysis
• Diagnosis of end stage liver disease
• Any unstable medical condition
• Use of chemotherapy or radiotherapy within 4 weeks before first dose of study dietary supplement
• Unwilling to stop dietary supplements 3 weeks before first dose of study dietary supplement

Where it is running

• Stanford University — Stanford, California, United States

Full record on ClinicalTrials.gov

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