Identification of Critical Thermal Environments for Aged Adults

Recruiting now · Early Phase 1

Conditions studied: Aging

In brief

This study evaluates critical environmental limits (temperature and humidity) above which older adults are unable to effectively thermoregulate. Participants will exercise in a series of different environmental conditions to identify combinations of temperature and humidity above which age-related physiological changes cause uncompensable heat stress, resulting in increased risk of heat illness.

Key facts

Study ID

NCT04284397

Run by

Penn State University

People needed

190

Starts

2020-12-30

Expected to finish

2027-02-27

Last updated by the study team

2026-01-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults aged 18 and older (those 40+ years of age must be cleared by collaborating physician)
• All premenopausal women will be eumenorrheic (by survey)
• Asymptomatic and no signs/symptoms of disease according to the American College of Sports Medicine 10th edition Guidelines for Exercise Testing and Prescription

You may not qualify if…

• Medications that affect thermoregulatory or cardiovascular responses to exercise
• Any contraindications to low intensity physical activity on the Physical Activity Readiness Questionnaire
• Any mobility restrictions that interfere with low intensity physical activity
• Pregnant or planning to become pregnant in the next 12 months
• Prior diagnosis of cancer, cardiovascular disease, diabetes, or metabolic syndrome
• Illegal/recreational drug use
• History of Chron's disease, diverticulitis, or similar gastrointestinal disease
• Abnormal resting or exercise electrocardiogram (ECG)

Where it is running

• Noll Laboratory — University Park, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.