Noninvasive Brain Stimulation for Pain Relief

Status unconfirmed · Not applicable

Conditions studied: Pain, Acute, Pain, Chronic, Pain, Experimental

In brief

Non-invasive brain stimulation techniques, transcranial magnetic stimulation (TMS) and transcranial focused ultrasound (FUS), is be applied to healthy human subjects, acute pain patients, and chronic pain patients to investigate their uses for pain relief.

Key facts

Study ID

NCT04283643

Run by

University of Virginia

People needed

149

Starts

2019-04-01

Expected to finish

2021-04-01

Last updated by the study team

2020-02-25

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adults between 18 and 80 years of age.
• Chronic and Acute pain patients: must have an MRI (for ultrasound targeting)

You may not qualify if…

• Direct report to the study team member
• History of brain surgery
• History of seizure
• Pregnant
• Have alcohol consumption exceeding 50 drinks/month
• Have history of opioid abuse (all subjects), or any recent opioid use (healthy controls)
• Have implant like pacemaker and aneurysm clip
• Current of psychiatric disease such as anxiety or depression, which is not optimally treated
• Current infection
• Current wound on the skin of upper and lower extremities
• Chronic pain patients: current chronic pain is not optimal controlled by pain medications (i.e. Pain VAS >5)

Where it is running

• University of Virginia — Charlottesville, Virginia, United States (enrolling)

Full record on ClinicalTrials.gov

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