Caffeine Study for Pain Control Following Total Joint Replacement
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Pain, Postoperative
In brief
A prospective, double blinded, single center, randomized controlled study to evaluate the efficacy of caffeine in combination with acetyl salicylic acid (ASA) in the management of postoperative pain in patients undergoing total joint arthroplasty.
Key facts
- Study ID
- NCT04280263
- Run by
- Rothman Institute Orthopaedics
- People needed
- 70
- Starts
- 2020-02-28
- Expected to finish
- 2021-08-01
- Last updated by the study team
- 2020-10-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient is older than 18 years old at the time of the surgery.
- Patient is treated by Rothman Orthopaedics institute and is scheduled for the surgical procedure at AtlantiCare Regional Medical Center.
- Patient is undergoing total hip or total knee arthroplasty.
- Patient has the diagnosis of Osteoarthritis of the hip or the knee, or other noninflammatory disease that results in joint damage to the hip or the knee.
You may not qualify if…
- Patient has known history of opioid addiction and/or has taken opioids preoperatively.
- Patient has history of cardiac diseases that might be aggravated by the use of caffeine, as diagnosed by a cardiologist or demonstrated by an abnormal EKG.
- Patient has a known allergy to aspirin or caffeine.
- Patient has history of chronic pain that required the intervention of a pain management doctor.
- Patient has an active infection at the time of surgery (systemic or localized) or history of chronic infections that affected the lower extremities.
- Patient has history of cancer that would affect patient reported outcomes including pain.
- Patient has history of neuropathic pain or nerve degenerative disease.
- Patients undergoing revision surgery would be excluded.
- Patients who require alternate DTV prophylaxis other than ASA.
Where it is running
- Rothman Orthopaedics at Egg Harbor Township — Egg Harbor, New Jersey, United States
Full record on ClinicalTrials.gov
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