Testing Different Modes of Cognitive Behavior Therapy
Completed · Not applicable
Conditions studied: Depression, Literacy
In brief
The purpose of this study is to test a novel behavioral treatment - Adapted Cognitive-Behavior Therapy (ACBT) - against standard Cognitive Behavior Therapy (CBT). The goal of the study is to determine if ACBT confers improved outcomes for women with depression and low literacy. Depression is a serious women's health issue. According to the World Health Organization, depression is the leading cause of disability worldwide with females reporting symptoms of depression at almost twice the rate of males. This study will provide pilot data to enable us to determine the effect size needed to detect a between-groups change in depression scores. The overall impact of this study will be empirical support for a novel form of treatment for women with depression, who also may lack adequate literacy, educational, or cognitive ability required to benefit from standard CBT.
Key facts
- Study ID
- NCT04279028
- Run by
- Northwestern University
- People needed
- 22
- Starts
- 2020-02-14
- Expected to finish
- 2023-11-15
- Last updated by the study team
- 2024-02-29
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- 18 years of age or older
- female
- diagnosis of major depressive disorder (MDD) according to DSM-5 (Diagnostic and Statistical Manual-5) (and no specifiers that pertain to exclusionary criteria (e.g. MDD with psychotic features)
- able and willing to give informed consent
- able to communicate in English
- willingness to be randomized to therapy
- willing to complete all study assessments
- at baseline, no plans to move from the Chicago area during the duration of the study
You may not qualify if…
- history of bipolar disorder
- history of psychosis
- current substance use disorder of moderate or severe level of severity
- suicidal intentions or actions within the past three months
- known neurologic disease (e.g., multiple sclerosis, Parkinson's disease, cerebrovascular accident) and/or cognitive or neurologic impairment (e.g., Alzheimer's disease)
- current participation in other psychotherapy (not including psychiatric appointments pertaining to medication management)
- inadequate vision or hearing to interact with study materials
- being a prisoner, detainee, or being in police custody
- any current involvement in litigation
Where it is running
- James W. Griffith — Chicago, Illinois, United States
Full record on ClinicalTrials.gov
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