Mindfulness-Based Relapse Prevention for Opioid and Alcohol Use Disorders
Completed · Not applicable
Conditions studied: Opioid-use Disorder, Opioid Abuse, in Remission, Alcohol Use Disorder, Alcohol Use Disorder, in Remission
In brief
A randomized controlled trial will examine mindfulness-based relapse prevention (MBRP) program outcomes for 240 individuals who have completed treatment for opioid or alcohol use disorders. MBRP is a group aftercare program that integrates mindfulness skills training with cognitive-behavioral relapse prevention strategies. Primary outcomes will include frequency of opioid/alcohol use, craving, withdrawal, and quality of life. Secondary outcomes include time to first opioid/alcohol use, adherence to medication-assisted treatment plans, perceived stress, posttraumatic stress symptoms, and chronic pain. We will also examine the following potential moderators of intervention outcomes: comorbid diagnoses, life events history, and MBRP intervention adherence. In addition, we will examine the following mediators of intervention outcome: mindfulness skills, emotion regulation skills, executive functioning skills, savoring, and positive and negative affect.
Key facts
- Study ID
- NCT04278352
- Run by
- Clemson University
- People needed
- 11
- Starts
- 2020-07-01
- Expected to finish
- 2023-08-01
- Last updated by the study team
- 2024-03-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- over 18 years of age
- completed behavioral health treatment for Opioid Use Disorder (OUD) or Alcohol Use Disorder (AUD) within the previous eight weeks
- continues to be followed by a behavioral health provider
- meets DSM-5 criteria for OUD or AUD
- English fluency
- able to attend intervention sessions
You may not qualify if…
- current psychosis
- dementia
- moderate to severe traumatic brain injury
- pregnancy
- active suicidality
- persistent antisocial behavior
- acute episode of an SUD (past two weeks)
- persistent self-injury requiring clinical management
- already completed or attending a mindfulness-based intervention
Where it is running
- Clemson University — Clemson, South Carolina, United States
- Prisma Health-Upstate Internal Medicine Clinic — Greenville, South Carolina, United States
- Phoenix Center — Greenville, South Carolina, United States
Full record on ClinicalTrials.gov
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