Evaluation of Sports Supplements on Blood Flow
Completed · Not applicable · Has a placebo group
Conditions studied: Determine the Effects of Nitrosigine and Citrulline-malate on Flow-mediated Dilation Among Young Adults
In brief
Many athletes seek to increase their plasma (blood) nitric oxide content prior to exercise in order to augment vasodilation. Increased vasodilation during exercise, especially high intensity resistance training, allows for more blood flow to muscle tissues, which may give the athlete benefits such as increased work capacity and acute muscle hyperemia, which is commonly referred to as muscle pump. Pre-workout supplements are typically taken 30 minutes to 1 hour prior to the onset of exercise, so the current investigation seeks to determine if citrulline malate or nitrosigine can effect vasodilation within 1 hour of supplementation, and if so, which supplement is more effective. Based on previous findings, we hypothesize that a certain exercise intensity needs to be present for citrulline malate and nitrosigine to have an effect, so a change may not be observable at rest.
Key facts
- Study ID
- NCT04278053
- Run by
- University of Arkansas, Fayetteville
- People needed
- 24
- Starts
- 2018-10-15
- Expected to finish
- 2019-05-08
- Last updated by the study team
- 2022-05-24
Who can join
Age: 18 and older, up to 29. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy, regularly exercising young adults
You may not qualify if…
- hypertension, metabolic disorders, previous consumption of pre-workout supplements 6 months prior to study, prescriptions medications known to effect the vasodilatory response.
Where it is running
- University of Arkansas — Fayetteville, Arkansas, United States
Full record on ClinicalTrials.gov
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