Rosacea and Ivermectin

Completed · Phase 2

Conditions studied: Rosacea

In brief

The primary hypothesis is that weekly digital interactions and routine measurement of Transepidermal Water Loss (TEWL) rates and Subcutaneous hydration levels will promote patient adherence to maintenance ivermectin therapy and prevent disease relapse. The project will consist of a trial in which thirty subjects with rosacea receive ivermectin therapy and are randomized to receive either no intervention, a weekly digital survey to assess patient's attitudes towards ivermectin therapy, or a portal hydration measurement device that measures TEWL rates and SC hydration levels. The study team will measure adherence objectively in all groups with electronic monitors attached to the containers of the ivermectin, which all subjects will be told to use daily for maintenance therapy. Additionally, the hydration measurement device can transmit data to an Internet server via a smartphone using Bluetooth technology, thereby allowing providers to monitor a patient's TEWL rate and SC levels.

Key facts

Study ID

NCT04275999

Run by

Wake Forest University Health Sciences

People needed

30

Starts

2021-04-16

Expected to finish

2025-01-17

Last updated by the study team

2026-03-27

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subject is 18 years of age or older.
• Subject has a working knowledge of English.
• Subject with a diagnosis of Rosacea
• Subjects without a known allergy to ivermectin
• Subjects with access to a smart phone

You may not qualify if…

• Subjects under 18 years of age.
• Subject does not have a working knowledge of English.
• Subject with a diagnosed skin condition other than rosacea
• Subjects with a known allergy to ivermectin
• Subjects without access to a smart phone

Where it is running

• Wake Forest Health Sciences Dermatology — Winston-Salem, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.