Intention Treatment for Anomia

Completed · Not applicable

Conditions studied: Aphasia, Stroke

In brief

Every year approximately 15,000 Veterans are hospitalized for stroke, and up to 40% of those Veterans will experience stroke-related language impairment (i.e., aphasia). Stroke-induced aphasia results in increased healthcare costs and decreased quality of life. As the population of Veterans continues to age, there will be an increasing number for Veterans living with the aphasia and its consequences. Those Veterans deserve to receive aphasia treatment designed to facilitate the best possible outcomes. In the proposed study, the investigators will investigate optimal treatment intensity and predictors of treatment response for a novel word retrieval treatment. The knowledge the investigators gain will have direct implications for the selecting the right treatment approach for the right Veteran.

Key facts

Study ID

NCT04267198

Run by

VA Office of Research and Development

People needed

32

Starts

2021-05-24

Expected to finish

2025-09-30

Last updated by the study team

2025-10-22

Who can join

Age: 21 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English as primary language
• > 6 months post-onset a left-hemisphere stroke. Multiple strokes are acceptable as long as they are confined to the left hemisphere.
• Diagnosis of aphasia
• Presence of word retrieval deficits
• Adequate comprehension as judged by ability to complete two-step commands on the Western Aphasia Battery.

You may not qualify if…

• Severe apraxia of speech or dysarthria
• Clinically significant depression
• For MRI safety: implanted medical devices, metal in the body and claustrophobia.

Where it is running

• Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur, Georgia, United States

Full record on ClinicalTrials.gov

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