The INVADE Study: INnominate Vein Approach for Central Catheterization in Difficult to cannulatE Patients

Recruiting now · Not applicable

Conditions studied: Critical Illness

In brief

Most recent guidelines suggest central venous access must be performed with real-time ultrasound guidance, and the most recommended site for cannulation is internal jugular vein (IJV); however, it is recognized that evidence for other sites is, at present, limited. Besides, guidelines does not account for patients with small vein cross-sectional area and/or respirophasic collapse, which can make the procedure more difficult or even impossible. The investigators aim to compare three different insertion sites for central venous access, with real-time ultrasound guidance

Key facts

Study ID

NCT04265703

Run by

Hospital Civil de Guadalajara

People needed

315

Starts

2024-02-27

Expected to finish

2027-02-28

Last updated by the study team

2026-03-12

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who need central venous catheterization, and have respirophasic variation in cross-sectional area of jugular veins

You may not qualify if…

• Less than 18 years-old
• Patients with previous failed attempts with non-ultrasound guided technique
• Non-resolved pneumothorax/hemothorax at enrollment
• Refusal to sign informed consent

Where it is running

• Hospital Civil Fray Antonio Alcalde — Guadalajara, Mexico (enrolling)

Full record on ClinicalTrials.gov

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