Wayfinding Intervention in High-Fidelity Long-Term Memory

Completed · Not applicable · Has a placebo group

Conditions studied: Long-Term Memory Decline, Mild Cognitive Impairment

In brief

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

Key facts

Study ID

NCT04253587

Run by

University of California, San Francisco

People needed

50

Starts

2019-10-01

Expected to finish

2021-12-15

Last updated by the study team

2023-02-27

Who can join

Age: 62 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• fluent speakers of English
• completed 12 or more years of education
• normal or corrected-to-normal vision
• dexterity to comfortably operate the scanner-compatible response box
• freedom from physical and neurological conditions contra-indicated for fMRI
• must confirm physical stamina and comfort for 45-minute, brisk walks on level ground

You may not qualify if…

• use of psychotropic medications
• history of concussions or dizziness, vestibular or balance problems
• significant discomfort with virtual reality experiences

Where it is running

• UCSF Mission Bay — San Francisco, California, United States

Full record on ClinicalTrials.gov

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