Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)

Recruiting now · Not applicable

Conditions studied: Smokers, Chronic Obstructive Pulmonary Disease

In brief

Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs. The impact on the health system of undiagnosed patients, up to 70% of patients, is increasingly documented. However, systematic spirometry screening remains controversial among smokers in the absence of data to link the detection of new patients with improved management and clinical events and health goals. More generally, there is little data on the evolution of patients in real life once they have entered the care system. The premise is that with systematic screening in general medicine, it is possible to identify the evolution of newly diagnosed COPD patients, to distinguish the different possible evolutions according to the initial phenotype and the management.

Key facts

Study ID

NCT04252781

Run by

Assistance Publique - Hôpitaux de Paris

People needed

300

Starts

2020-08-20

Expected to finish

2026-02-20

Last updated by the study team

2025-01-09

Who can join

Age: 35 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Inclusion criteria of smokers with spirometry (pre-inclusion)
• Age> 35 years
• Smoking > 20 PA
• Active smoking (cessation < 1 month)
• Signature of consent to participate in Phase I of the study
• Inclusion criteria for patients with incidental COPD
• FEV1 / FVC <70% of the theoretical value and / or <LLN (Lower limit of normal)
• Signature of consent to participate in Phase II of the study

You may not qualify if…

• Known COPD
• Cancer being treated
• No affiliation to the social security or other social protection scheme
• Pregnant or lactating woman
• Patient deprived of liberty or under legal protection (under tutorship or curatorship

Where it is running

• Hopital Henri MONDOR — Créteil, Île-de-France Region, France (enrolling)

Full record on ClinicalTrials.gov

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