Home Air Purification for Eosinophilic COPD

Completed · Not applicable · Has a placebo group

Conditions studied: COPD, Eosinophilia

In brief

This study evaluates the influence of home air purification on the lung health of adults with eosinophilic COPD. Half of the participants will receive real air purifiers (HEPA filters) and half will receive sham air purifiers.

Key facts

Study ID

NCT04252235

Run by

Beth Israel Deaconess Medical Center

People needed

178

Starts

2021-03-15

Expected to finish

2026-02-28

Last updated by the study team

2026-03-04

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age of 40 years or more
• Physician diagnosis of COPD [Global Initiative for Obstructive Lung Disease (GOLD) Stage II-IV disease with Forced Expiratory Volume (FEV1)/ Forced Vital Capacity (FVC) ≤70% and FEV1 (% predicted) <80%]
• Blood eosinophil count of >=150 cells per μL at screening or in the previous year
• Former smoker with tobacco exposure of >=10 pack-years

You may not qualify if…

• Inability to complete monthly questionnaires
• Inability to perform lung function testing
• Regularly using a portable HEPA air purifier in the home at time of enrollment
• End stage chronic disease with life expectancy <2 years as determined by PI judgment
• Living in location other than home (e.g. long term care facility)
• Planning to change residence within the study period

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.