Early Intervention in Infants With Cerebral Palsy

Recruiting now · Not applicable

Conditions studied: Cerebral Palsy

In brief

Contractures are a frequent cause of reduced mobility in children with Cerebral palsy (CP) already at the age of 2-3 years. Reduced muscle use and muscle growth have been suggested as key factors in the development of contractures, suggesting that efficient early prevention will have to involve stimuli that can facilitate muscle growth already before the age of 1 year. The present study protocol was developed to assess the effectiveness of an early intervention program, CONTRACT, on muscle growth and mobility in children at very high risk of CP compared with best standard care.

Key facts

Study ID

NCT04250454

Run by

University of Copenhagen

People needed

36

Starts

2021-05-20

Expected to finish

2029-12-01

Last updated by the study team

2024-05-09

Who can join

Age: 0 and older, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Infants younger than 17 weeks CA with suspicion of brain lesion determined from a medical assessment, by MRI or ultrasound scan or abcent fidgety movements (FM) determined as part of General Movement Asessement (GMA) will be included. The brain lesion should be rated severe enough by the clinician to have informed the parents of the associated risk of CP.

You may not qualify if…

• Infants otherwise eligible but with severe genetic abnormalties, severe heart problems, metabolic diseases, or still hospitalized will not be selected for the study.

Where it is running

• Elsass Foundation — Charlottenlund, København City, Denmark (enrolling)

Full record on ClinicalTrials.gov

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