An Efficacy and Safety Study of Ravulizumab in ALS Participants

Stopped early · Phase 3 · Has a placebo group

Conditions studied: Amyotrophic Lateral Sclerosis, ALS

In brief

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

Key facts

Study ID

NCT04248465

Run by

Alexion Pharmaceuticals, Inc.

People needed

382

Starts

2020-03-30

Expected to finish

2021-10-17

Last updated by the study team

2023-01-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Neuromuscular Research Center and Clinic — Phoenix, Arizona, United States
• HonorHealth Research Institute — Scottsdale, Arizona, United States
• Loma Linda University Medical Center — Loma Linda, California, United States
• University of Southern California — Los Angeles, California, United States
• University of California-Irvine — Orange, California, United States
• Stanford University Medical Center — Palo Alto, California, United States
• University of California San Diego Medical Center — San Diego, California, United States
• Norris MDA/ALS Center — San Francisco, California, United States
• University of California San Francisco Medical Center — San Francisco, California, United States
• University of Colorado Anschutz Medical Campus School of Medicine — Aurora, Colorado, United States
• University of Florida at Shands Jacksonville — Jacksonville, Florida, United States
• University of South Florida — Tampa, Florida, United States
• University of Chicago Medical Center — Chicago, Illinois, United States
• Indiana University Medical Center — Indianapolis, Indiana, United States
• University of Kansas Medical Center Research Institute, Inc. — Kansas City, Kansas, United States
• University of Kentucky — Lexington, Kentucky, United States
• Johns Hopkins University School Of Medicine — Baltimore, Maryland, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• Las Vegas Clinic — Las Vegas, Nevada, United States
• Beth Israel Medical Center - PRIME — New York, New York, United States
• Hospital for Special Surgery — New York, New York, United States
• Atrium Health Neuroscience Institute — Charlotte, North Carolina, United States
• The Cleveland Clinic Foundation — Cleveland, Ohio, United States
• The Ohio State University — Columbus, Ohio, United States
• Barrow Neurological Institute — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.