Ketamine for Post-operative Analgesia in Hemorrhoidectomy

Recruiting now · Phase 4

Conditions studied: Hemorrhoids

In brief

This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.

Key facts

Study ID

NCT04248205

Run by

University of Oklahoma

People needed

100

Starts

2020-06-15

Expected to finish

2027-07-01

Last updated by the study team

2026-04-01

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-100
• Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids.

You may not qualify if…

• Inability to undergo general anesthesia
• Contraindications to hemorrhoidectomy
• History of schizophrenia or other hallucinatory psychiatric illnesses
• History of psychosis
• Chronic narcotic usage defined as either having a pain contract with a pain management specialist and no narcotic usage for one month prior to hemorrhoidectomy.

Where it is running

• University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States (enrolling)

Full record on ClinicalTrials.gov

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