Inhibitory Control: Effects of Modulation

Completed · Not applicable · Has a placebo group

Conditions studied: Young Adults

In brief

Inhibitory control is relevant to many clinical disorders, including substance abuse/dependence, obsessive-compulsive disorder, and attention-deficit hyperactivity disorder. This proposal is designed to assess brain networks related to response inhibition in healthy young adults, and use neuromodulation to change these networks and behavioral performance on a response inhibition task. Having an understanding of the brain mechanisms involved in response inhibition may enable us to improve pre-existing treatments for disorders with inhibitory control difficulties.

Key facts

Study ID

NCT04247334

Run by

Butler Hospital

People needed

117

Starts

2019-11-14

Expected to finish

2024-02-25

Last updated by the study team

2026-06-08

Who can join

Age: 18 and older, up to 25. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Low (<1sd below the mean on the BRIEF-Inhibit) or high (>1sd above the mean on BRIEF-Inhibit scale)
• English fluency to ensure comprehension of study measures and instructions.

You may not qualify if…

• Presence of medical conditions contraindicated for tDCS, including history of any known intracranial pathology, epilepsy or seizures, traumatic brain injury, brain tumor, stroke, implanted medical devices, current pregnancy or women of childbearing age not using effective contraception, or any other serious medical conditions or health problems that would interfere with participation (e.g., skin condition)
• Inability to undergo MRI
• Current substance abuse disorder
• Currently prescribed psychiatric medications.
• Active mania or psychosis

Where it is running

• Butler Hospital — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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