Effects of Fish Oil and Resistance Training on Muscle Mass and Function

Paused · Not applicable · Has a placebo group

Conditions studied: Fat-free Masss, Muscle Strength, Neuromuscular Function

In brief

This study consists of a free-living, 6-week fish oil (FO) or placebo (PLA) supplementation intervention alongside participants' habitual resistance exercise training (RET) regimens. Twenty young, healthy resistance-trained subjects who do not currently supplement with FO will be recruited to participate. An eligible participant will be between ages 18 and 35 and will have a minimum of two years of RET experience. Participants will be randomized into a FO group and a PLA group. The FO group will supplement with 4g/day of FO (4g fish oil concentrate: 2g EPA+ 1g DHA) and the PLA group will consume 4g/day of coconut oil (saturated fatty acids), as administered via gel capsules, in conjunction with their current RET program. Prior to intervention all participants will complete baseline biometric, strength, and neuromuscular testing. Participants will also have blood drawn to test for omega-3 fatty acid status, and complete and return a 3-day diet record and a physical activity recall. In order to monitor adherence to supplementation, FO and PLA bottles will also be returned weekly and pills will be counted. 3-day diet records will be obtained to ensure calorie and protein intakes remain consistent throughout the intervention period. Weekly physical activity records will also help to ensure consistency of participant training and to make sure all participants are following their training regimes in a progressive fashion. Following 6 weeks of FO or PLA supplementation, subjects will repeat all initial biometric, strength and neuromuscular testing, as well as a second, post-intervention blood draw.

Key facts

Study ID

NCT04245332

Run by

Rowan University

People needed

20

Starts

2020-01-29

Expected to finish

2021-09-30

Last updated by the study team

2021-03-10

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Young, healthy, resistance-trained men and women of all nationalities between the ages of 18-35

You may not qualify if…

• metabolic disease (diabetes or metabolic syndrome)
• cardiovascular disease
• pulmonary disease
• chronic inflammatory conditions (e.g. renal/kidney, liver, asthma, arthritis, autoimmune diseases, inflammatory bowel disease)
• neurological conditions (e.g. Parkinson's)
• sexually transmitted diseases
• cancer diagnosis within the previous 5 years
• currently smoking cigarettes
• hypertension
• hypercholesterolemia and/or dyslipidemia
• using medications to manage cholesterol, blood lipids, blood pressure, or diabetes
• taking performance-enhancing drugs and/or anabolic agents (e.g. testosterone, growth hormone, or beta-2 agonists)
• oral contraceptive use, are pregnant, or intend to become pregnant while enrolled in the study
• fish oil supplement use within the past 6 months
• fasting blood total cholesterol concentration >200mg/dl
• fasting blood glucose concentration >100mg/dl

Where it is running

• Rowan University — Glassboro, New Jersey, United States

Full record on ClinicalTrials.gov

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