Validation of a Novel Cortical Biomarker Signature for Pain

Completed

Conditions studied: TMD

In brief

The study aims to undertake analytical validation of an brain biomarker in healthy participants experiencing a model of sustained temporomandibular pain. The biomarker could detect participants at greater risk of developing more severe pain.

Key facts

Study ID

NCT04241562

Run by

University of Maryland, Baltimore

People needed

159

Starts

2020-11-04

Expected to finish

2022-10-10

Last updated by the study team

2023-04-04

Who can join

Age: 18 and older, up to 44. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy

You may not qualify if…

• unable or refusal to provide written consent
• presence of any acute pain disorder
• history or presence of any chronic pain disorder
• history or presence of any other medical or psychiatric compliant
• use of opioids or illicit drugs in the past 3 months
• pregnant or lactating women
• excessive alcohol use
• contraindicated for TMS (metal implants, epilepsy)

Where it is running

• University of Maryland School of Dentistry — Baltimore, Maryland, United States
• Neuroscience Research Australia — Sydney, New South Wales, Australia

Full record on ClinicalTrials.gov

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