Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
Status unconfirmed · Not applicable
Conditions studied: Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity, Knee Pain Swelling, Muscle Weakness, Muscle Weakness Condition, Power
In brief
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy. The researchers will utilize a sample of convenience with consecutive sampling at the Brooke Army Medical Center physical therapy clinic for patients referred for knee osteoarthritis. As is standard of care, patients will be provided a medical intake form and a clinical outcome measure commensurate with their primary anatomic region for which they are seeking physical therapy (i.e.: Lower Extremity Functional Scale for hip, knee, or ankle pain). If patients choose to partake in the study, they will complete the consent form and the initial physical therapy evaluation will be conducted. They will then be provided an appointment for data collection at the Army-Baylor Center for Rehabilitation Research biomechanics lab at the Army Medical Department Center and School. The treatment group will receive one 30-minute session of orthopedic manual physical therapy targeting the knee joint and soft tissues with complementary exercises targeted at their impairment. The control group will receive a 30-minute class on knee OA diagnosis, prognosis, various treatment options, and will conclude with a question and answer with the researcher. Both groups will receive their intervention from a board-certified physical therapist in the Army-Baylor Orthopedic Manual Therapy Fellowship program. At the conclusion of formal testing, the patient will be provided standard physical therapy care as deemed appropriate by their evaluating physical therapist. Thus, all subjects, regardless of their assigned group, will receive the same standard of care for their knee pain.
Key facts
- Study ID
- NCT04234282
- Run by
- Jennifer Moreno Clinic
- People needed
- 40
- Starts
- 2020-01-01
- Expected to finish
- 2020-07-01
- Last updated by the study team
- 2020-01-21
Who can join
Age: 45 and older, up to 74. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age range including 50-70 years old
- Diagnosis of clinical and radiographic knee osteoarthritis (Altman's Criteria: knee pain, osteophytes and one of the following: crepitus with active motion, morning stiffness less than or equal to 30 minutes, bony enlargement)
- Grade 2-4 Kellgren Lawrence radiographic knee osteoarthritis
- Able to tolerate maximal quadriceps isometric quadriceps contraction with the knee flexed to 60 degrees without pain increasing more than 3/10 points on the Numeric Pain rating scale
- English proficiency and cognition to understand explanations of research purpose and procedures
- Tricare beneficiary
You may not qualify if…
- Knee pain referred from another anatomic region
- Cardiovascular disease (limited to uncontrolled hypertension/arrhythmias as well as a pacemaker
- Rheumatoid arthritis
- Active cancer
- BMI > 35
- Intra-articular knee injection within the previous 3 months
- Traumatic knee injury or surgery in past 12months
- Total knee or hip arthroplasty
- Gait is limited to a greater extent by conditions other than knee osteoarthritis
- Any condition that would contraindicate manual therapy or exercise
- Medical "red flags" of a potentially serious condition including cauda equina syndrome, major or rapidly progressing neurological deficit, fracture, active infection, or systemic disease
- Known current pregnancy or history of pregnancy in the last 6 months
- Separating from the military in the next 2 months, pending litigation, or pending medical board
Where it is running
- Jennifer Moreno Clinic — Fort Sam Houston, Texas, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.