Preoperative Tamsulosin to Prevent Postoperative Urinary Retention After Surgery For Pelvic Floor Disorders

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Urinary Retention

In brief

Our hypothesis is that patients receiving preoperative Tamsulosin will have decrease rates of postoperative urinary retention (POUR) after surgery in females for pelvic floor disorders.

Key facts

Study ID

NCT04232683

Run by

The Cleveland Clinic

People needed

100

Starts

2019-12-18

Expected to finish

2025-10-11

Last updated by the study team

2026-05-26

Who can join

Age: any. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• i. Patient undergoing surgery for prolapse with or without mid-urethral sling procedure.
• ii. Specific surgical procedures include all vaginal, laparoscopic and robotic reconstructive or obliterative surgeries including the use of mid-urethral slings

You may not qualify if…

• i. Diagnosis of urinary retention preoperatively (post void residual >150ml)
• ii. Malignancy
• iii. History of neurological disease
• iv. History of spinal cord injuries
• v. Allergy to Tamsulosin
• vi. Perioperative complications requiring prolonged postoperative bladder drainage
• vii. Incontinence procedures other than mid-urethral slings

Where it is running

• Cleveland Clinic Florida — Weston, Florida, United States

Full record on ClinicalTrials.gov

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