Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans

Completed · Phase 4

Conditions studied: Human Microbiome

In brief

The purpose of the research is to find out the effect of commonly used topical antibiotics on the bacteria that live in the nose, throat and on the skin of older adults. In addition, the investigators want to determine if these topical antibiotics affect how bacteria are spread in Community Living Centers of the VA Maryland Health Care System.

Key facts

Study ID

NCT04218799

Run by

University of Maryland, Baltimore

People needed

19

Starts

2014-08-12

Expected to finish

2015-09-22

Last updated by the study team

2023-06-06

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 50 years or older.
• Living in a participating nursing home for at least 80% of the past 3 months-
• Willing to provide anterior nares, posterior pharynx, skin and throat specimens over the study period.
• Willing to use intranasal mupirocin and topical chlorhexidine over a five day period.
• Provide signed and dated informed consent from subject or LAR.

You may not qualify if…

• Recent history of MRSA colonization
• Use of mupirocin nasal ointment in past 3 months
• Use of topical chlorhexidine in past 3 months
• History of an allergic reaction to chlorhexidine or mupirocin

Where it is running

• Loch Raven VA Community Living Center — Baltimore, Maryland, United States
• Perry Point VA Community Living Center — Perry Point, Maryland, United States

Full record on ClinicalTrials.gov

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