EsophaCap for the Detection of Early Esophageal Carcinoma

Recruiting now

Conditions studied: Barrett Esophagus, Esophageal Cancer, Gastric Cancer

In brief

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.

Key facts

Study ID

NCT04214119

Run by

Johns Hopkins University

People needed

2500

Starts

2016-01-12

Expected to finish

2028-12-19

Last updated by the study team

2025-12-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Undergoing esophagogastroduodenoscopy at Johns Hopkins Hospital from 1/2016 to 12/2025
• Age greater than 18 years
• Patients must be able to swallow a capsule

You may not qualify if…

• Patients in either arm with extra-esophageal malignancies including head and neck and gastric cancer
• Patients who have undergone esophagectomy
• Patients who have undergone radiation to the chest
• Patients who are younger than 18
• Patients with esophageal stents
• Patients with esophageal strictures disabling passage of the capsule

Where it is running

• Bayview Medical Center — Baltimore, Maryland, United States (enrolling)
• Johns Hopkins Hospital — Baltimore, Maryland, United States (enrolling)

Full record on ClinicalTrials.gov

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