Improving Adherence to Rabies PEP Guideline Recommendations

Completed · Not applicable

Conditions studied: Rabies, Rabies Human, Rabies Virus Infection

In brief

This quasi-experimental, quality improvement study will be conducted across the Houston Methodist system, including all hospital-based and freestanding emergency departments (ED). Previous research identified opportunities to improve patient selection and delivery of rabies immune globulin (IG) as recommended by Centers for Disease Control and Prevention (CDC) guideline recommendations for rabies postexposure prophylaxis (PEP). The purpose of this study is to develop, implement, and measure the impact of a quality improvement bundle that consists of (1) rabies PEP electronic health records (EHR) enhancements, (2) education to ED staff, and (3) education to patients. Adherence to quality indicators, which are based on CDC guideline recommendations, for patient selection and delivery of rabies IG for 12 months following implementation (post-implementation group) will be compared with a historical control group.

Key facts

Study ID

NCT04213950

Run by

The Methodist Hospital Research Institute

People needed

70

Starts

2019-12-29

Expected to finish

2020-12-23

Last updated by the study team

2021-09-05

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Receive at least one dose of rabies IG or rabies vaccine at a study site during the study period

Where it is running

• Houston Methodist Emergency Department at Baytown — Baytown, Texas, United States
• Houston Methodist Emergency Care Center in Cypress — Cypress, Texas, United States
• Houston Methodist Hospital Emergency Department — Houston, Texas, United States
• Houston Methodist Emergency Care Center at Voss — Houston, Texas, United States
• Houston Methodist Emergency Department at Willowbrook Hospital — Houston, Texas, United States
• Houston Methodist Emergency Department at West — Houston, Texas, United States
• Houston Methodist Emergency Care Center at Kirby — Houston, Texas, United States
• Houston Methodist Emergency Care Center in Sienna Plantation — Missouri City, Texas, United States
• Houston Methodist Emergency Department at Clear Lake — Nassau Bay, Texas, United States
• Houston Methodist Emergency Care Center in Pearland — Pearland, Texas, United States
• Houston Methodist Emergency Care Center in Cinco Ranch — Richmond, Texas, United States
• Houston Methodist Emergency Care Center in Spring — Spring, Texas, United States
• Houston Methodist Emergency Department at Sugar Land — Sugar Land, Texas, United States
• Houston Methodist Emergency Care Center in The Woodlands — The Woodlands, Texas, United States
• Houston Methodist Emergency Department at The Woodlands — The Woodlands, Texas, United States

Full record on ClinicalTrials.gov

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