Identification of Best Postoperative Analgesia Method Following a Minimally Invasive Repair of Pectus Excavatum
Running, not enrolling · Not applicable
Conditions studied: Pectus Excavatum, Pain, Postoperative
In brief
Pectus excavatum is the most common chest wall deformity in children, accounting for 90% of all congenital chest wall deformities. It occurs in one to eight per 1000 live births. The severity of the pectus deformity may become more noticeable during pubertal growth spurs and repair is therefore usually performed in the teenage years. A common operative procedure to repair a pectus deformity is the minimally invasive repair of pectus excavatum (MIRPE). The MIRPE involves the substernal placement of a contoured metal bar secured to the lateral aspect of the ribs. This metal bar allows for correction of the concave deformity by applying constant outward pressure to the underside of the sternum. Although the cosmetic results are excellent, patients do report significant pain from the constant pressure exerted on the chest wall from the metal bar. Pain management approaches tend to differ on both the provider and institutional level. There is a lack of evidence regarding which postoperative analgesia method is best. To address this research gap, this proposal aims to conduct a randomized controlled trail using the three most commonly used methods; 1) patient controlled analgesia (PCA); 2) erector spinae blocks (ESB) with continuous infusion pumps; and 3) video-assisted intercostal nerve cryoablation (INC).
Key facts
- Study ID
- NCT04211935
- Run by
- University of Colorado, Denver
- People needed
- 158
- Starts
- 2020-05-27
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-04-28
Who can join
Age: 12 and older, up to 21. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- All patients with a pectus excavatum deformity that will undergo a MIRPE procedure will be included in the study.
You may not qualify if…
- < 12 years old
- > 21 years old
- chronic narcotic preoperative use
- previous repair of pectus excavatum deformity
- previous thoracic surgery
- pregnancy
Where it is running
- Children's Hospital Colorado — Aurora, Colorado, United States
Full record on ClinicalTrials.gov
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