A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With Asthma
Completed · Phase 4 · Has a placebo group
Conditions studied: Asthma
In brief
The primary objective of the study is to demonstrate that dupilumab treatment improves exercise capacity in patients with moderate-to-severe asthma. The secondary objectives of the study are: * To demonstrate that dupilumab treatment increases physical activity of daily living in patients with moderate-to-severe asthma * To demonstrate that dupilumab treatment improves pre- and post-exercise lung function in patients with moderate-to-severe asthma
Key facts
- Study ID
- NCT04203797
- Run by
- Regeneron Pharmaceuticals
- People needed
- 40
- Starts
- 2020-07-16
- Expected to finish
- 2023-07-15
- Last updated by the study team
- 2024-04-18
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Palos Verdes Medical Group (PVMG); Peninsula Research Associates (PRA) — Rolling Hills Estates, California, United States
- UCLA Medical Center - Harbor — Torrance, California, United States
- Allianz Research Institute — Westminster, California, United States
- University of Iowa Hospitals & Clinics-Roy J. and Lucille A. Carver College of Medicine — Iowa City, Iowa, United States
- University Of Kansas Medical Center — Kansas City, Kansas, United States
- Infinity Medical Research — North Dartmouth, Massachusetts, United States
- University of Michigan — Ann Arbor, Michigan, United States
- American Health Research — Charlotte, North Carolina, United States
- UH Cleveland Medical Center — Cleveland, Ohio, United States
- Temple University Hospital — Philadelphia, Pennsylvania, United States
- Regeneron Study Site — Hendersonville, Tennessee, United States
- The University of Texas Medical School at Houston — Houston, Texas, United States
- Intermountain Medical Center — Murray, Utah, United States
- CHU Dijon — Dijon, Bourgogne-Franche-Comté, France
- CHU Reims — Reims, Marne, France
- CHU de Strasbourg - Nouvel Hopital Civil — Strasbourg, France
- Praxis Dr. M. Rolke u. Dr. P. Rueckert — Aschaffenburg, Bavaria, Germany
- Regeneron Study Site — Frankfurt am Main, Hesse, Germany
- IKF Pneumologie GmbH & Co. KG - Institut fuer klinische Forschung Pneumologie Frankfurt (Clinical Research Centre Respiratory Medicine) to IKF Pneumologie Frankfurt GmbH & Co KG. — Frankfurt am Main, Hesse, Germany
- Regeneron Study Site — Hanover, Lower Saxony, Germany
- Regeneron Study Site — Koblenz, Rhineland-Palatinate, Germany
- IKF Pneumologie Mainz, Helix Medical Excellence Center Mainz — Mainz, Rhineland-Palatinate, Germany
- Regeneron Study Site — Großhansdorf, Schleswig-Holstein, Germany
- KLB - Gesundheitsforschung Luebeck GmbH — Lübeck, Schleswig-Holstein, Germany
- Regeneron Study Site — Berlin, Germany
Full record on ClinicalTrials.gov
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