Glucose Variability and Cognition in Prediabetes

Recruiting now

Conditions studied: Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, Functional Status, PreDiabetes, Aging, Depression

In brief

This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.

Key facts

Study ID

NCT04201600

Run by

University of Maryland, Baltimore

People needed

30

Starts

2022-03-01

Expected to finish

2026-12-31

Last updated by the study team

2025-03-30

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 50 years and older
• At least 8th grade education

You may not qualify if…

• Diagnosed type 1 or type 2 diabetes
• Current use of mediation for diabetes (oral hypoglycemic agents, insulin), or with diabetic properties (e.g., steroids)
• Chronic disorders (cardiovascular disease, peripheral vascular disease, stroke, transient ischemic attack, chronic kidney disease, past year cancer)
• Neurological disorders (e.g., Parkinson's, epilepsy, multiple sclerosis)
• History of dementia or suspected dementia
• Known HIV
• Serious mental illness, psychosis, or use of psychotropic medication
• Heavy alcohol use

Where it is running

• Baltimore VA Geriatric Research Education and Clinical Center (GRECC) — Baltimore, Maryland, United States (enrolling)

Full record on ClinicalTrials.gov

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